Hazell TJ, Gallo S, Vanstone CA, Agellon S, Rodd C, Weiler HA (2016) Pediatr Obes. 2016 Feb ijpo.12105. [Epub ahead of print]
OBJECTIVES: Evaluate how vitamin D supplementation in infancy affects body composition at 3 years of age.METHODS: Double-blind randomized trial of 132, 1-month-old healthy, breastfed infants randomly assigned to receive oral vitamin D3 supplements of 400, 800, 1200 or 1600 IU d-1 for 11 months. In the present analysis, 87 (66%) returned at 3 years of age. Body composition was measured using dual-energy x-ray absorptiometry and plasma 25-hydroxyvitamin D [25(OH)D] concentrations by liquid chromatography tandem mass spectrometry.
CONCLUSIONS: Higher vitamin D status from infancy through to 3 years of age associates with leaner body composition.© 2016 World Obesity. Pediatric Obesity.