Research on gut-brain communication via the immune system may help in the development of novel treatments for neurodegenerative diseases.
Research on gut-brain communication via the immune system may help in the development of novel treatments for neurodegenerative diseases. The findings were presented at Neuroscience 2019, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.
There is now an increased understanding of the connection between the almost 100 trillion microbes in the intestine (i.e., the "gut" microbiome) and the brain. Recent studies suggest that intestinal bacterial imbalance is connected to disorders like allergies, obesity, cancer, and neurodegenerative diseases like Alzheimer's disease (AD) and traumatic brain injury (TBI). As this relationship becomes better understood, so too does the potential to use this connection to ameliorate the pathology of neurological diseases.
Today's new findings show that:
"These are important contributions to our understanding of the complex relationship between the gut and the brain," said press conference moderator Jane A. Foster, Ph.D., an associate professor at McMaster University who studies the role of immune-brain and gut-brain interactions on neurodevelopment.
"The evidence suggests that manipulating gut health can also impact brain health in relevant ways, and that microbiome balance corresponds to improved immune functioning. Continued research in this area has the potential to give us more treatment options for neurodegenerative diseases in the future."