FAB RESEARCH COMMENT:
This systematic review of 14 randomised controlled trials, including almost 5000 patients, found benefits for cognitive function in older adults from dietary supplementation with a combination of omega-3 fatty acids and B vitamins (with or without other nutrients).
Nutrients work in synergy, not in isolation, and previous clinical trials have already indicated that in patients with mild cognitive impairment or early-stage dementia, adequate supplies of both
omega-3 EPA/DHA and certain B vitamins are needed to slow cognitive decline and prevent physical brain shinkage - and that neither in isolation has the same benefits. See for example:
Other clinical trials have also shown benefits for slowing cognitive decline in early-stage Alzheimer's from supplementation with omega-3 and a broad range of micronutrients in addition to B vitamins. See: