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Fast fructose consumption overwhelms the gut and leads to fatty liver

A new multi-centre study in mice has explained the mechanism behind how excessive consumption of fructose can 'overwhelm' the gut and lead to fatty liver disease, revealing the importance of fructose consumption timing.


Cannabis offers immediate relief from symptoms of depression: study

Depression is the most common mental health disorder in the U.S., affecting roughly one in five adults and is at the core of numerous other health conditions including cancer, substance use disorders, anxiety disorders, schizophrenia, dementia, diabetes, cardiovascular disease, chronic pain, and other physical disabilities. Until recently, there has been little research on the actual effects of common and commercially available cannabis products on mood and behavioral motivations more generally.


Abnormal proteins in the gut could contribute to the development of Alzheimer's disease

A new study published in the Journal of Physiology has shown that misfolded protein build-up in the gut could contribute to the development of Alzheimer's-like symptoms in mice. This could suggest a new treatment approach for Alzheimer's disease that would target the gut before symptoms of cognitive deficits appear in patients. As these proteins were found in the gut, which is a window to the world, this suggests environmental factors might be contributing to cognitive deficits seen in Alzheimer's disease and other conditions.


Oat and rye bran fibres alter gut microbiota, reducing weight gain and hepatic inflammation

In a newly published experimental study, the consumption of dietary fiber from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation. In addition, diets enriched with oat or rye bran were shown to attenuate weight gain. The effects of oat and rye were partly different, but both were beneficial for health.


Fussy eating—and parents' stress—remedied by online guide

Parents battling their children's fussy eating have been given fresh hope thanks to an online resource proven to relieve the problem. With around half of toddlers and young children turning their noses up at certain foods—often healthy fruit and vegetables—many families face stressful mealtimes. And parents' reactions, often using unhealthy foods as a 'reward' or limiting access to them, can be counter-productive and lead to bad habits that last into adulthood.


Brain iron accumulation linked to cognitive decline in Alzheimer's patients

Iron accumulation in the outer layer of the brain is associated with cognitive deterioration in people with Alzheimer's disease.


Researchers find on-off switch for inflammation related to overeating

Researchers have identified a molecule that plays a key role in the body's inflammatory response to overeating, which can lead to obesity, diabetes, and other metabolic diseases. The finding suggests that the molecule could be a promising therapeutic target to control this inflammation and keep metabolic diseases in check.


Light drinking may protect brain function

Light to moderate drinking may preserve brain function in older age, according to a new study from the University of Georgia. The study examined the link between alcohol consumption and changes in cognitive function over time among middle-aged and older adults in the U.S.


Antioxidant cocktail key to preventing Alzheimer's

Diet rich in nutrients and antioxidants may prevent or even reverse the effects of Alzheimer's disease


24 June 2020 - MedicalXpress - Addressing the safety of high folate levels in the older population and implications for fortification in Ireland

A new study led by researchers from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin challenges claims from some international scientific circles, that having high blood levels of folate (folic acid) increases the risk of poor cognition in older adults, especially in those with low levels of vitamin B12.


24 June 2020 - MedicalXpress - Medicinal cannabis may reduce behavioral problems in kids with intellectual disabilities

Cannabidiol, a type of medicinal cannabis, may reduce severe behavioural problems in children and adolescents with an intellectual disability a new study has found.


18 June 2020 - MedicalXpress - Creating a new paradigm for understanding the individual effects of diet

Researchers have made a major breakthrough in understanding how individuals can have different reactions to the same diets.


Stem cell study shows how fish oil may help with depression

A stem cell study into the effectiveness of different antidepressants has concluded fish oil creates an antidepressant response similar to that seen from prescribed medicines.


15 June 2020 - Karolinska Institute - New findings explain how 'indigestion' medications can increase dementia risks

Millions of people around the world use proton pump inhibitors for conditions like heartburn, gastritis and stomach ulcers. Researchers at Karolinska Institutet in Sweden now report that the long-term use of these drugs could increase the risk of developing dementia.


People born small for gestational age have a lower IQ throughout development from infancy to adulthood

People born small for gestational age (SGA) have a lower IQ throughout development, however the differences in IQ to those born appropriate for gestational age (AGA) reduce by adulthood. The effects of SGA on IQ are nearly as large as being born into lower socio-economic status or receiving poor parenting in infancy.


9 June 2020 - MedicalXpress - Antioxidants in brain linked to improved psychosis treatment

Patients with higher levels of an antioxidant called glutathione respond more quickly to medication for psychosis and have improved outcomes. It is estimated that a 10 percent increase in antioxidants could lead to a reduction in length of hospital stay by at least seven days.


4 June 2020 - MedicalXpress - Temperament affects children's eating habits

Children who are what we often think of as temperamental, are particularly vulnerable to developing eating habits that can lead to unhealthy weight gain and difficulties with food and eating.


New gut-brain link: how gut mucus could help treat brain disorders

Mucus is the first line of defence against bad bacteria in our gut. But could it also be part of our defence against diseases of the brain?


18th May 2020 - Gut-brain axis: Microbiome linked to neuron disease

Harvard University scientists have identified a new gut-brain connection in amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND), through a study in mice. The researchers found that in mice with a common ALS genetic mutation, changing the gut microbiome using antibiotics or faecal transplants could prevent or improve disease symptoms.


15 May 2020 - MedicalXpress - Chemists develop foolproof new test to track the fats we eat

A team of researchers at McMaster University has developed a reliable and accurate blood test to track individual fat intake, a tool that could guide public health policy on healthy eating.